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POST-DOCTORAL POSITION
Harvard Medical School/Brigham and Women's Hospital

Cutting edge projects focusing on the mechanisms of autoimmune disease/inflammation. These projects include novel pathways that regulate macrophages, and T cells, macrophage biology linked to lupus, determining the unique and shared role of the principle macrophage developmental molecule and its isoforms in immune mediated inflammation and lupus, the power of the specific programmed death pathways in regulating tissue injury, and an emphasis on the role of resident cells in regulating the immune response. Unique transgenic strains and knockout mice with reporter genes have been constructed on lupus susceptible strains for these projects. These projects dissect the basic mechanisms of autoimmune (skin, heart, kidney). Projects include human translational studies in patients with lupus. The ultimate goal is to identify potential therapeutic targets/ biomarkers for lupus and by extension other immune mediated diseases.

Experience:
Immunology, Molecular biology and/or Cell Biology
Knowledge of histopathology desirable
Mouse systems
Computer literacy is necessary

Desired:
Responsible, hard-working individual who is able to multi-task and to work independently.

Position available immediately.

MD, or PhD required, position for two years or longer within the Department of Medicine, Brigham and Women’s Hospital.

Please send three references.

Interested candidates contact:
Dr. Vicki Rubin Kelley
Harvard Institutes of Medicine
4 Blackfan Circle
Boston, MA 02115
FAX 617-525-5830
e-mail: vkelley@rics.bwh.harvard.edu


Therakos, Inc., a member of Johnson & Johnson's Family of Companies, is recruiting for a MEDICAL SCIENCE LIAISON (MSL), based in a major East Coast city.

Therakos, Inc. specializes in extracorporeal immune cell therapies for the prevention and treatment of serious immune-mediated and neoplastic diseases. Therakos' proprietary procedures in photopheresis are used by physicians for the palliative treatment of the skin manifestations of cutaneous T-cell lymphoma.

The MSL will build advocacy for the Company Extracorporeal Apheresis treatment with opinion leaders, key academic centers and professional organizations in the Eastern U.S. Region. The MSL will serve as a scientific and clinical support resource for Company. This includes directly communicating scientific and medical information during interactions with health care practitioners and pre-clinical researchers. Topic areas include: Stem Cell Transplantation, Apheresis, Dermatology, Hematology, Oncology and Immunology.

PharmD, MD or PhD is required. At least 1 year of pharmaceutical or medical device industry experience preferred. Prior MSL experience is desirable. Therapeutic area experience in oncology, hematology, dermatology and/or immunology is highly preferred. Travel up to 70%. See full job description on our website.

As a valued team member, you’ll receive a competitive salary and great benefits including medical/dental, a 401(k), a pension plan and a comprehensive wellness program. If interested, please apply directly on-line at our web site www.jnj.com/careers noting Req. Code 0807143. The Johnson & Johnson Family of Companies has a strong commitment to diversity and welcomes applications for all individuals. EOE M/F/D/V


Merck Serono - Senior Scientist - Immunology (B Cell biology) Geneva Research Center - 0800200

Purpose of the Role:
This position requires an experienced scientist with a track record in the field of human B cell biology and a good understanding of clinical strategies that target B cells. You will be expected to use your knowledge and experience to mentor staff and to drive scientific innovation and capability within the Immunology Group.

Main tasks & Responsibilities:
In this role, you will be expected to:
  • Supervise a laboratory in the Immunology Group and provide scientific expertise in the area of B cell biology. This will involve designing, directing and integrating research from different disciplines
  • Recognize and communicate trends/events outside the Company in the field of B cell therapy. Provide a long-term vision of the opportunities and strategy in the field of B cell targeting therapies and how this would add value to the business needs of Merck Serono.
  • Contribute to the development of novel therapeutics targeting B cells for the treatment of multiple sclerosis and other autoimmune and inflammatory disorders and contribute to shaping the research strategy.
  • Represent the Immunology function in various research projects in both inflammatory and autoimmune diseases and make significant contributions to multidisciplinary meetings.
  • Provide written reports and deliver effective presentations.
Education & Languages:
  • An M.D.or Ph.D. in Cell biology, Immunology or related fields.
  • Fluent english is required
  • French is an asset
Professional Skills & Experience:
  • A minimum of 5 years’ relevant postdoctoral experience.
Personal Skills & Competencies:
  • Excellent communication & interpersonal skills
  • Enthusiasm & team spirit

Merck Serono - Senior Scientist - Immunology (Cytokine biology) Geneva Research Center – 0800201

Purpose of the Role:
This position requires an experienced scientist with a track record in the field of cytokine biology and a good understanding of clinical strategies that target pro-inflammatory cytokines. You will be expected to use your knowledge and experience to mentor staff and to drive scientific innovation and capability within the Immunology Group.

Main tasks & Responsibilities:
In this role, you will be expected to:
  • Supervise a laboratory in the Immunology Group and provide scientific expertise in the area of cytokine biology. This will involve designing, directing and integrating research from different disciplines
  • Recognize and communicate trends/events outside the Company in the field cytokine-directed therapies. Provide a long-term vision of the opportunities and strategy in this field and understand how this would add value to the business needs of Merck Serono.
  • Contribute to the development of novel therapeutics targeting inflammatory cytokines and cytokine pathways for the treatment of multiple sclerosis and other autoimmune and inflammatory disorders and contribute to shaping the research strategy.
  • Represent the Immunology function in various research projects in both inflammatory and autoimmune diseases and make significant contributions to multidisciplinary meetings.
  • Provide written reports and deliver effective presentations.
Education & Languages:
  • An M.D. or Ph.D in Cytokine biology, Immunology or related fields.
  • Fluent english is required
  • French is an asset
Professional Skills & Experience:
  • A minimum of 5 years’ relevant postdoctoral experience.
Personal Skills & Competencies:
  • Excellent communication & interpersonal skills
  • Enthusiasm & team spirit

Merck Serono - Senior Scientist- Immunology (Inflammation) Geneva Research Center – 0800389

Purpose of the Role:
This position requires an experienced immunologist with a track record in the field of autoimmune and inflammatory diseases and a good understanding of clinical strategies targeting inflammatory pathways. Through close interaction with project managers and colleagues in other parts of the organization, the successful candidate will play a key role in our effort to establish and progress projects targeting inflammatory disorders, and to develop competencies in relevant area of Immunology.

Main Tasks & Responsibilities:
  • You will be responsible for a group of scientists, technicians and students.
  • This group will support ongoing drug discovery programs and will be engaged in identifying, evaluating and validating potential drugs targets for the treatment of rheumatoid arthritis, psoriasis and other autoimmune and inflammatory disorders.
  • This will involve close collaboration with other departments in the organization, including antibody production, identification low molecular weight compounds, in vivo pharmacology and bioinformatics.
  • You will be encouraged to use his existing personal network to contribute to the identification of new project opportunities from external partners in academia or in biotech industry.
Education & Languages:
  • PhD and/or PhD/MD in Immunology
  • Fluent english is required
  • French is an asset
Professional Skills & Experience:
  • A minimum of ten years relevant postdoctoral experience, preferably in the pharmaceutical industry in the area of immunology/inflammation research.
  • Small molecule and/or protein drug development experience would also be beneficial.
Personal Qualifications & Competencies:
  • Excellent communication and interpersonal skills
  • Enthusiasm and team spirit

Merck Serono - Senior Scientist- Immunology (T cell Biology) Geneva Research Center – 0800387

Purpose of the Role:
This position requires an experienced immunologist with a track record in the field of T-cell biology as reflected by high quality publications and a good understanding of clinical strategies targeting T-cell responses.

Main Tasks & Responsibilities:
  • You will supervise a laboratory focusing on the investigation of key pathways in immune cell/T cell regulation, activation, proliferation and suppressor functions.
  • This work will support on-going drug discovery programs and contribute to the identification and development of new drug candidates for the treatment of rheumatoid arthritis, psoriasis and other autoimmune and inflammatory disorders.
  • You will head a team of scientists, technicians and students, be responsible for running the laboratory, writing research reports and high quality publications, presenting to various internal boards and international science meetings.
Education & Languages:
  • PhD and/or PhD/MD in Immunology
  • Fluent english is required
  • French is an asset
Professional Skills & Experience:
  • A minimum of 5 years’ relevant postdoctoral experience, preferably in the pharmaceutical industry in the area of immunology and, in particular, human and mouse T cells.
  • In Depth understanding and state of art practical experience in cell activation, proliferation, as well as cytokine release and mastering FACS analysis and cell sorting is desirable.
Personal Qualifications & Competencies:
  • Excellent communication and interpersonal skills
  • Enthusiasm and team spirit

Post your career opportunities on the FOCIS website

Job posting rates:
$75 per posting – academic/non-profit/government
$125 per posting – industry

Job postings should be 250 words or less and will remain on the website for 90 days. To post your opportunities please contact Sarah Krause.



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