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Courses
Basic Immunology for Clinicians: Update 2006
Wednesday, May 31, 2006
8:00am-5:00 pm
San Francisco Marriott
This course is presented by in conjunction with the 6th Annual Meeting of the Federation of Clinical Immunology Societies (FOCIS 2006). Registration for Basic Immunology for Clinicians is separate from that of FOCIS 2006. You may register to attend the course alone, or as part of your FOCIS 2006 Registration.
Please register on-site for this course. The course fee is $150; MasterCard, Visa, American Express, check or cash will be accepted on-site. Please register at the Golden Gate Hall - A at the San Francisco Marriott. Continental breakfast will be served at 7:00 am, and the scientific program will begin at 8:00 am.
Objectives
At the conclusion of this course, attendees should have gained:
- An understanding of the fundamental mechanisms underlying immunologic diseases and the principles for therapeutic modulation of the immune system.
- An appreciation of the basic immunological principles underlying biotherapeutics, understand the commonality among diverse organ specific disease states, and understand the mechanisms of therapeutic effect.
- Improved ability to understand the medical literature reporting immunologic advances pertinent to their patients, to comprehend the rationale for use of new immunodiagnostic and immunotherapeutic modalities in their patients, and to serve as thought leaders within their medical community.
Course Schedule
Lecture 1: Innate Immunity
This lecture will provide an overview of innate immunity and its relationship to specific or adaptive immunity. The broad mechanisms by which pathogens are recognized as being both foreign and dangerous will be discussed.
Lecture 2: Antigen Presentation
This lecture will provide an overview of the nature of antigens and immune recognition for both cellular and humoral immunity and also describe the major pathways of antigen presentation to both helper and cytotoxic T cells.
Lecture 3: T-Cell Activation and Regulation
This lecture will summarize functional responses of T cells to antigen with focus on the role of signals provided by antigen, costimulators and cytokines, The differences in responses of naïve and effector T cells will be discussed, as well as mechanisms of homeostasis.
Lecture 4: Cell-Mediated Immunity
This lecture will cover T cell mediated immune responses in defense and disease. Topics will include the definitions and properties of T cell mediated immunity, stages of cell mediated immune responses, Th1 and Th2 subsets, cytolytic T lymphocyte (CTL) responses, and T cell memory.
Lecture 5: Lymphocyte Development
This lecture will address issues that relate to the development of T and B cells, the generation of immunological diversity, and the mechanisms by which T and B cells collaborate.
Lecture 6: Tolerance and Autoimmunity
This lecture will provide an overview of mechanisms of tolerance, including central (Thymic) and peripheral T cell Tolerance. The roles of AIRE, regulatory T cells, costimulation, and IL-2 will be discussed. Autoimmunity will be presented from the point fob view of the mechanisms of tolerance failure and genetic susceptibilities, with specific examples of autoimmune diseases provided.
Faculty
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Dr. Abul Abbas, MD Dr. Abbas received his MD from the All India Institute of Medical Sciences in India, completed training in Pathology at the Brigham & Women's Hospital and Harvard and joined the faculty at Harvard Medical School and the Brigham and Women's Hospital, where he rose to become Professor of Pathology and Head of the Immunology Research Division. In 1999, he moved to the University of California- San Francisco as Professor and Chairman of the Department of Pathology. Dr. Abbas has received several teaching awards at Harvard and UCSF, and numerous honors, including election to the Institute of Medicine of the National Academy of Sciences. He oversees an NIH funded laboratory in Immunology, with a focus on the control of immune responses, self tolerance and autoimmunity. He has published over 160 peer reviewed papers and invited reviews, and is an author of two widely used textbooks of Immunology, as well as Robbins & Cotran's Pathologic Basis of Disease. |
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Dr. Hidde Ploegh, PhD Dr. Ploegh is an acclaimed researcher whose work focuses on the immune system. Dr. Ploegh came to the Whitehead Institute for Biomedical Research from the Harvard Medical School where, as Professor of Pathology, he had been heading the school's immunology program since 1997. Prior to that, Dr. Ploegh was a Professor of Biology at MIT, working primarily in the Center for Cancer Research. Dr. Ploegh's research has contributed in many ways to the understanding of the immune system including the molecular mechanisms by which the body responds to antigens-substances such as toxins, bacteria, or foreign cells from transplants which, when entering the body, trigger the production of antibodies. Recently he's focused on viral protein interference with this process. Dr. Ploegh's 300-plus research papers include the June 24, 2004 cover story for the journal Nature, which described one of the mechanisms by which the immune system eliminates misfolded proteins. |
Accreditation Statement:
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the Clinical Immunology Society and FOCIS. The Clinical Immunology Society is accredited by the ACCME to provide continuing medical education for physicians.
The Clinical Immunology Society designates this educational activity for a maximum of seven (7) Category 1 credits toward the AMA Physician's Recognition Award. Each physician should claim only those credits that he/she actually spent in the activity.
This course made possible through an unrestricted educational grant from:
© 2008 FOCIS