Science and Speakers

Wednesday, June 6, 2007
*Basic Immunology for Clinicians* (additional fee) Register Now	8:00 am-5:00 pm
Abul K Abbas, MD Hidde Ploegh, PhD

Thursday, June 7, 2007 Member Society Satellites
FOCIS Centers of Excellence Trainee Satellite Symposia (invitation only)	8:00 am-5:00 pm
*Regulatory T Cells in Transplantation*	9:00 am-11:30 am
- American Society of Transplantation (pre-registration required)
*Damage Associated Molecular Pattern Molecules, Inflammation and Autoimmunity*	9:00 am-5:00 pm
- Clinical Immunology Society and International Society for Biological Therapy of Cancer (additional fee)
*Immunoassessment & Interventional Immunology*	9:00 am-5:00 pm
- Clinical Immunology Society and Cancer Vaccine Consortium (additional fee)
*TCR Repertoire and Structure in Type 1 Diabetes and Multiple Sclerosis Pathogenesis and Treatment*	9:00 am-5:30 pm
- International Society for NeuroImmunology and the Immunology of Diabetes Society (additional fee)
*Immune Response In Silico*	1:00 pm-4:00 pm
- American Academy of Allergy, Asthma & Immunology (pre-registration required)
*Ocular Inflammation: Hot Topics for 2007*	1:00 pm-5:00 pm
- American Uveitis Society (pre-registration required)
FOCIS Centers of Excellence Trainee Satellite Symposia Poster Reception	6:30 pm-9:30 pm

Friday, June 8, 2007
Poster Session - Authors Optional	7:30 am-8:30 am
Plenary: Combating Infectious Disease	8:30 am-10:00 am
Elite Controllers of HIV: Implications from Studies of Natural Control for HIV Vaccines, Bruce Walker, MD
Dancing with the Enemy: Tales of Host Defense to Herpes Virus, Carl Ware, PhD
Thematic Sessions	10:15 am-12:00 pm
Combination Therapies to Induce Tolerance Building on the Experience with CD3-specific Antibodies to Induce Tolerance in Autoimmunity, Lucienne Chatenoud, MD, PhD Abstract: Prevention and Treatment of Autoimmune Arthritis Using IL-12 Gene-silenced Dendritic Cells, Motohiko Suzuki, MD, PhD Pathways of B Cell Activation, Robert Carter, MD Overcoming T Cell Mediated Beta Cell Killing is the Clear Target, But How Do We Test Approaches to Hit It?, David Harlan, MD Commensal Flora and the Immune Response Bacterial Polysaccharides Provide for Symbiosis During Intestinal Colonization, Dennis Kasper, MD Abstract: Helicobacter Pylori in the Pathogenesis of Chronic Autoimmune Pancreatitis, Antonio Puccetti Commensal Flora and the Immune Response: The Role of TLR, Eyal Raz, MD Innate Immune Responses to Commensal Bacteria at Gut Epithelial Surfaces, Lara Hooper, PhD From Micro to Nano Imaging In Vivo Imaging of Islet Transplantation, Zdravka Medarova, PhD Antigen Transport of Follicular Dendritic Cells in Lymphnodes, Thorsten Memple, MD Using the Eye to Image the Immune Response, James Rosenbaum, MD Dynamics of the Unfolding EAE Lesion as Documented by Two-photon Real-time Imaging, Hartmut Wekerle, MD
Getting your First NIH Grant Funded (additional fee)	12:00 pm-1:00 pm
Writing a Successful NIH Grant, John Peyman, PhD Submitting an NIH Grant Successfully, Nancy Saunders, PhD Successful Outcome of the Review of Your NIH Grant, Larry Pease, PhD and V. Michael Holers, MD
Industry Tutorials	12:00 pm-1:00 pm
Plenary: Targeting B Cells	1:00 pm-2:30 pm
B Cells as Therapeutic Targets in Multiple Sclerosis, Amit Bar-Or, MD, FRCPC Targeting B Cells in Autoimmune Disease: New Insights, Bill St. Clair The Synovial Tissue Response to Rituximab Treatment: How Does it Relate to Clinical Response?, Paul-Peter Tak, MD, PhD
Oral Abstract Sessions	2:45 pm-4:45 pm
Regulatory T Cells I Therapy: Antigen Specific Autoantigens Stem Cell/Immunodeficiency/HIV
Keynote Symposium:	5:00 pm-5:45 pm
IL-6, Th17 and Treg: Why is Anti-IL6R Effective in Autoimmunity?, Tadamitsu Kishimoto, MD, PhD
Poster & Exhibition Hall Open	5:30 pm-7:30 pm
Poster Session with Authors Present	5:45 pm-7:00 pm
Opening Reception - Exhibition Hall	7:30 pm-9:00 pm

Saturday, June 9, 2007
Poster Session - Authors Optional	7:30 am-8:30 am
Poster & Exhibition Hall Open	7:30 am-8:30 am
Plenary: Crucial Novel Cytokine Pathways	8:30 am-10:00 am
Cytokine Targeting in Inflammatory Synovitis, Iain McInnes, MRCP, PhD Anti-TNFs in the Clinics - What are They Telling Us About TNF Biology?, Andrew Nesbitt, PhD
Thematic Sessions	10:15 am-12:00 pm
Inflammation Good or Bad for Tregs Cross Talk Between Antigen-specific Effectors (Th17) and CD4+,CD25+, Fox-P3+ Regulatory T Cells in the Inflamed Target Tissue, Vijay Kuchroo, DVM, PhD Abstract: Viral Infection Enables Regulatory T Cells to Protect From Autoimmune Diabetes, Christophe Filippi Control of the In Vivo Inflammatory Response by the Chemolcore, Gary Graham, PhD Targeting TNFa in Rheumatoid Arthritis: Allowing Tregs to Prevail, Mike Ehrenstein, PhD Immunodeficiencies in Humans - Human 'Knockouts' BAFF-receptor Deficiency Impairs Human B Cell Development, Hermann Eibel, PhD Abstract: From FoxP3 Mutation to IPEX (Immune Dysfunction, Polyendocrinopathy, Enteropathy, X-linked): Genotype-Phenotype, Pathogenic Mechanisms and Therapeutic Options, Elenora Gambineri, MD The Clinical Presentation and Molecular Basis of IPEX (Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked), Hans Ochs, MD Herpetic Encephalitis in Children: New Immune Defects, Emmanuelle Jouanguy, PhD Immune Responses to Modified Self Antigens FOCIS Lifetime Achievement Award: Recipient: Eli Sercarz, PhD Presentation of Award: Linda Wicker, PhD Modification of Myelin Basic Protein, Eli Sercarz, PhD Citrullination: Target of Pathogenic Autoimmunity in Rheumatoid Arthritis, V. Michael Holers, MD Celiac Disease: Sandwiched Between Adaptive and Innate Immunity, Frits Koning, PhD Oxidation - Specific Epitopes are Important Targets of Innate Immunity, Joe Witztum, MD
Industry Tutorials	12:00 pm-1:00 pm
Poster & Exhibition Hall Open	12:00 pm-2:00 pm
Plenary: Developing Immunotherapies	1:00 pm-2:30 pm
NF-kB in Immune & Inflamatory Responses, Sankar Ghosh, PhD Tilting the Balance of Immunity Toward Tolerance, Terry Strom, MD Advances in Immunotherapy for Allergy and Asthma, David Broide, MD, ChB
Oral Abstract Sessions	2:45 pm-4:45 pm
Pathogenicity of Th17 and Th1 Therapy: From Gene Silencing to Costimulation Biomarkers & New Technologies New Animal Models of Disease Immunoregulatory Mechanisms
Presidential Address The Genetic Control of Regulatory T Cells, David Hafler, MD	5:00 pm-5:45 pm
Poster & Exhibition Hall Open	5:30 pm-7:30 pm
Poster Session with Authors Present	5:45 pm-7:00 pm
Under the Stars Reception for Trainees	7:00 pm-9:00 pm

Sunday, June 10, 2007
Industry Tutorials	7:00 am-8:00 am
Poster Session - Authors Optional	7:30 am-8:30 am
Poster & Exhibition Hall Open	7:30 am-8:30 am
Plenary: Innovative Immunotherapies	8:30 am-10:00 am
The Future of Adoptive Immunotherapy for Cancer, Nick Restifo, MD TWEAKing Inflammatory Disease by a Multifunctional Cytokine, Linda Burkly, PhD
Thematic Sessions	10:15 am-12:00 pm
From Genes to Treatment - supported by the Clinical Immunology Society Cryopyrin, Interleukin-1, and Inflammatory Disease, Hal Hoffman, MD Toll-like Receptor Polymorphisms & the Innate Immune Response to Infection, Tom Hawn, MD, PhD Old Cytokines, New Disease Targets: Type 1 Interferon and Interleukin 1, Virginia Pascual, MD Antigen Specific Immune Modulation Human Tumor Antigens can Distort the Balance Between Innate and Adaptive Immunity that can be Restored by Vaccination, Olja Finn, PhD Abstract: Neurofascin-specific Autoantibodies Mediate Axonal Injury in Inflammatory Demyelinating Diseases of the Central Nervous System, Christopher Linington Epitope Specific Immunotherapy in Rheumatoid Arthritis, Salvo Albani, MD, PhD DNA Vaccines for Autoimmune Diseases: Preclinical and Clinical Results, Hideki Garren, MD, PhD Innate Immunology The Inflammasome, Jurg Tschopp, PhD Abstract: IL-23 is Required for Induction of an Innate Immune Response to Citrobacter Rodentium, Darrell O.Quinn Genetic Analysis of Innate Immunity in Mice, Bruce Beutler, MD PRRs and Activation of Autoroactive B Cells, Ann Marshak-Rothstein, PhD
Editor’s Lunch Session (additional fee)	12:00 pm-1:00 pm
Preparing your Manuscripts for Maximum Impact, Ushma Neill, PhD, Journal of Clinical Investigation What’s in the Black Box? JEM’s New Guidelines for Flow Cyometric Data, Heather van Epps, PhD, Journal of Experimental Medicine Clinical and Experimental Immunology: Translation as a Tradition, Mark Peakman, MD, PhD, Clinical and Experimental Immunology
Industry Tutorials	12:00 pm-1:00 pm
Poster & Exhibition Hall Open	12:00 pm-2:00 pm
Plenary: Emerging Vaccine Strategies	1:00 pm-2:30 pm
Analysis of Immune Responses Against Influenza and Pox Viruses, Alex Sette, PhD Exploiting Epithelial-Dendritic Cell Interactions for Induction of Mucosal Immunity, Marian Neutra, PhD Pharmacologic Control of Toll-like Receptor 7 Activation, Dennis Carson, MD
Oral Abstract Sessions	2:45 pm-4:45 pm
Regulatory T Cells II Genetics Cytokine/Chemocine Regulations of Inflammation & Allergy Regulating Inflammation
Keynote Address	5:00 pm-5:45 pm
IBD2007: A Model Disease for Merging Basic, Translational and Clinical Science, Stephan Targan, MD
Poster & Exhibition Hall Open	5:30 pm-7:30 pm
Poster Session with Authors Present	5:45 pm-7:00 pm

Monday, June 11, 2007
Network of Consortia Day

The Genes That Cause Autoimmune Disease
Introduction, Francis Collins, MD, PhD
Wellcome Trust Case Control Consortium, Lon Cardon, PhD
Type I Diabetes, John Todd, PhD
Validating Nucleic Acid Biomarkers by Mass Spectrometry, Charles Cantor, PhD
International Multiple Sclerosis Genetic Consortium, Philip De Jager, MD, PhD
North American Rheumatoid Arthritis Consortium, Peter Gregersen, MD
Swedish Rheumatoid Arthritis Consortium, Mark Seielstad, PhD
An Introduction to Illumina's Large-scale Infinium Whole-genome SNP Genotyping and DNA Copy Number Analysis Products, Carsten Rosenow, PhD
Inflammatory Bowel Disease Genetic Consortium, Judy Cho, MD
IMAGEN Consortium-Examination of the MHC in Autoimmune Diseases, John Rioux, PhD
The Affymetrix 6.0, 1.8 Million Markers for the Future of Genetic Research, Tom Willis, PhD
GWA: What is Now, What is the Future, Teri Manolio, MD, PhD

8:00 am-12:00 pm