Federation of Clinical Immunology Societies - FOCIS 2008: Registration & Housing

Final Program | CME/Attendance Certificate | Abstracts Online

FOCIS 2008: PRELIMINARY SCIENTIFIC PROGRAM

PLEASE NOTE: All sessions and speakers are preliminary and subject to change.

Wednesday, June 4, 2008
Registration Open	3:00 pm-6:00 pm
Basic Immunology in Medicine: Update 2008 (Requires additional registration fee)	8:30 am-4:45 pm

Thursday, June 5, 2008
Registration Open	7:00 am-5:00 pm
Interventional Immunology Course (Requires additional registration fee)	7:00 am-5:50 pm
FOCIS Centers of Excellence Trainee Satellite Symposium (Invitation only)	8:30 am-5:30 pm
FOCIS Member Society Satellite Symposia (Requires additional registration fee)	8:00 am-5:00 pm
Role of the Immune System in Chronic and Degenerative Ocular Disease – presented by the American Uveitis Society (AUS)	8:30 am-12:30 pm
Immune Monitoring in Transplantation—From Benchside to Bedside - presented by the American Society for Histocompatibility & Immunogenetics (ASHI), The Transplantation Society (TTS) & American Society of Transplantation (AST)	8:30 am-12:30 pm
Immunoassessment - presented by the Clinical Immunology Society (CIS)	8:30 am-5:30 pm
Primary Immunodeficiency Diseases Consortium Conference - presented by the Clinical Immunology Society (CIS), Section of Clinical Immunology & Allergy of the Royal Society of Medicine (RSM), European Society of Immunodeficiency (ESID), National Institute of Allergy & Infectious Diseases (NIAID) & the Office of Rare Diseases	8:30 am-5:30 pm
Antigen Recognition at Mucosal Surfaces: Implications for Allergic, Inflammatory & Immunologic Diseases - presented by the Society for Mucosal Immunology (SMI), American Academy of Allergy, Asthma & Immunology (AAAAI) & Crohn’s & Colitis Foundation of America (CCFA)	8:30 am-5:30 pm
Dendritic Cells and B Cells in MS and Type 1 Diabetes: From Basic Research to Clinical Trials - presented by the International Society for Neuroimmunology (ISNI)/Immunology of Diabetes Society (IDS)	9:00 am -4:15 pm
Emerging Cytokine-Based Therapies – presented by the International Cytokine Society (ICS)	1:00 pm -5:30 pm
Improving Vaccination for Chronic Viral Infections - A Case for Emerging Immune Modulatory Therapies - presented by the Clinical Immunology Society (CIS)	1:00 pm-5:30 pm
FOCIS Centers of Excellence Trainee Satellite Symposia Poster Party (Invitation only)	5:00 pm-7:00 pm

Friday, June 6, 2008
Registration Open	7:00 am-5:00 pm
Plenary Session Lessons in Immunodeficiencies From Pediatric Infectious Diseases to Novel Primary Immunodeficiencies, Jean Laurent Casanova, MD, PhD, University of Paris Defects in B Cell Development: An Update, Mary Ellen Conley, MD, St. Jude Children’s Research Hospital Molecular Defects in Severe Combined Immunodeficiency and Lessons Learned Following Immune Reconstitution, Rebecca Buckley, MD, Duke University Medical Center	8:30 am-10:00 am
Concurrent Thematic Symposia Mast Cells, Basophils & Eosinophils in Inflammatory Disease Pulmonary CXCR2 Regulates VCAM-l Dependent, Antigen-Induced Recruitment of Mast Cell Progenitors to Lung, K. Frank Austen, MD, Brigham & Women's Hospital Eosinophils Mediate Early Alum Adjuvant-Elicited B Cell Priming and IgM Production, Haibin Wang, Harvard Medical School Mast Cell-Dependent Limitation of Pathology Associated with Innate and Acquired Immune Responses, Stephen J. Galli, MD, Stanford University School Medicine Basophils and Mast Cells Play Distinct Roles in Acute and Chronic Allergic Responses, Hajime Karasuyama, MD, PhD, Tokyo Medical and Dental University Graduate School	10:15 am-Noon
Novel Cytokines Balancing Immunity and Inflammation in the Gut, David Artis, PhD, University of Pennsylvania IL-22 is Required for Th17 Cell Mediated Skin Inflammation in Murine Model of Psoriasis, Hakling Margery Ma, Wyeth Research Cytokine Regulation of Autoimmune Diseases, Daniel Cua, PhD Mechanism of Regulatory T Cell Function, Dario Vignali, PhD, St. Jude Children’s Research Hospital	10:15 am-Noon
Achieving & Measuring Transplant Tolerance Mechanisms of Tolerance Achieved with Combined Organ and Bone Marrow Transplantation, Megan Sykes, MD, Massachusetts General Hospital/Harvard Medical School A New Combined Therapy (anti-CD45RB mAb + rapamycin + IL-10) Able to Induce Active Long-term Tolerance in a Stringent Pre-clinical Model of Allogeneic Islet Transplantation, Nicola Gagliani, Raffaele Scientific Institute Role of Dendritic Cells in Transplant Immunity, Miriam Merad, MD, PhD, Mount Sinai Mechanistic Studies of Tolerant Renal Transplant Recipients, Kenneth A. Newell, MD, PhD, Emory University	10:15 am-Noon
Industry Tutorials	Noon-1:00 pm
Professional Tool Kit Sessions: Presentation Skills, Getting Funded & Getting Published	Noon-1:00 pm
Plenary Session Antigen Presentation: Loading & Exposing Pathogens & Tumors Regulation of the Immune Response by Dendritic Cells, Ira Mellman, PhD, Yale University, School of Medicine Antigen Presentation by CD1: Distinct Timing for CD1 and MHC in Anti-microbial Response, Michael B. Brenner, MD, Brigham & Women’s Hospital The Contribution of the Immune System to the Efficacy of Chemotherapy in Cancer, Laurence Zitvogel, MD, PhD, Institut Gustave Roussy	1:00 pm-2:30 pm
Oral Abstract Sessions Immune Pathways Uncovered in Immunodeficiency Shaping Immune Cell Function Achieving Tolerance Linking Innate & Adaptive Immunity Regulatory T Cell Function	2:45 pm-4:45 pm
Keynote Session: Dendritic Cells and Vaccine Biology Ralph M. Steinman, MD, Rockefeller University	5:00 pm -5:45 pm
Poster Session with Authors Present	5:45 pm-7:00 pm
Opening Reception (open to all delegates)	6:00 pm-8:00 pm

Saturday, June 7, 2008
Registration Open	7:00 am-5:00 pm
Plenary Session Tolerance & Autoimmunity: New Mechanisms and Therapeutic Targets Molecular Control of Immunological Tolerance, Diane Mathis, PhD, Joslin Diabetes Center Regulation of Immunity and Autoimmunity, Richard Flavell, PhD, Yale University School of Medicine Targeting Interferon-a in Rheumatic Diseases, Barbara White, MD, MedImmune, Inc.	8:30 am -10:00 am
Concurrent Thematic Symposia Translating Regulatory T Cells into the Clinic Regulatory T Cells and Type 1 Diabetes, Jane Hoyt Buckner, MD, Benaroya Research Institute Expansion of Allogeneic CD4+ CD25high FoxP3+ Regulatory T Cells by Human Colonic Myofibroblasts, Irina Pinchuk, University of Texas Medical Branch Therapeutic Applications of Tregs, Jeffrey A. Bluestone, PhD, University of California San Francisco Regulatory T Cell Immunotherapy for Tolerance to Self Antigens and Alloantigens in Humans, Maria Grazia-Roncarolo, MD, PhD, San Raffaele Telethon Institute for Gene Therapy	10:15 am -Noon
Key Cytokines in Autoimmunity TSLP, OX40L, and IL-25 - the Axis of Allergy, Yong-Jun Liu, MD, PhD, Center for Cancer Immunology Research Expression of RORC2 Controls the Development of Human Th17 Cells, Megan Levings, University of British Columbia Cytokine Signal Transduction and T Cell Differentiation, John J. O’Shea, MD, NIAMS/NIH Inflammatory Pathways in Psoriasis, James Krueger, MD, PhD, The Rockefeller University	10:15 am -Noon
Translational Uses of Humanized Mice Antibody Responses in Human Immune System Mice, Hergen Spits, PhD, Genentech Anti-CD20 Therapy Delays or Prevents Recurrent Type 1 Diabetes in NOD Mice, Changyun Hu, Yale University School of Medicine Humanized Mice to Study Vaccines, Karolina Palucka, MD, PhD, Baylor Institute for Immunology Research Humanized Mouse Models of Skin Inflammation, Frank Nestle, MD, Kings College London	10:15 am -Noon
Industry Tutorials	Noon -1:00 pm
Plenary Session Communicating Danger: Inflammatory Mediators Th17 Development and Regulation, Casey T. Weaver, MD, University of Alabama - Birmingham Molecular and Functional Anatomy of the Inflammatory Reflex, Kevin Tracey, MD, North Shore-Long Island Jewish Research Institute T Cell Differentiation, Migration and Immune Regulation, Federica Sallusto, PhD, Institue for Research in Biomedicine	1:00 pm-2:30 pm
Oral Abstract Sessions Differentiation of Th17 and Regulatory T Cells New Therapeutic Approaches Drivers & Suppressors of Autoimmunity Targeting B Cells	2:45 pm-4:45 pm
Keynote Session Interleukin-1 beta, the Caspase-1 Inflammasome and Treating Autoinflammatory Disease Charles Dinarello, MD, University of Colorado	5:00 pm - 5:45 pm
Poster Session with Authors Present	5:45 pm-7:00 pm
Trainee Reception (open to all delegates)	7:00 pm-9:00 pm

Sunday, June 8, 2008
Registration Open	7:00 am-10:00 am
Plenary Session Immunologic Modulation for Cancer Therapy Immune Checkpoint Blockade in Cancer Therapy, James P. Allison, PhD, HHMI/Memorial Sloan Kettering Cancer Center Engineering T Cells for Cancer Immunogene Therapy, Carl June, MD, University of Pennsylvania Targeting Cancer with T Cells - Size is Not All That Matters, Philip Greenberg, MD, University of Washington	8:30 am-10:00 am
Concurrent Thematic Symposia Innovations in Genetic Approaches Genomics of Tolerance, Christophe Benoist, Harvard University Flt3, a New Regulator of IL-10 Production by Human T Cells, Identifies using an RNAi Library, Anne Astier, Harvard Medical School T Cell Recognition and the Regulation of Sensitivity, Mark M. Davis, PhD, Stanford University Translating Genetic Advances to the Clinic, Judy Cho, MD, Yale University	10:15 am-Noon
Movers & Shakers: Cellular Migration and Immunomodulation Trafficking, Motility and T Cell Behavior, Christopher Hunter, PhD, University of Pennsylvania Control of CD103- Myeloid DC Trafficking Through CD47 is Critical for the Development of TH2 Mediated Allergic Inflammation, Marianne Raymond, Université de Montréal Regualtion of T Cell Responses in Leishmaniasis, David Sacks, PhD, NIH – National Institute of Allergy and Infectious Diseases HIV Disease Progression: Immune Activation, Microbes and a Leaky Gut, Daniel C. Douek, MD, PhD, NIH	10:15 am-Noon
Lessons from Microbe-Host Interactions Forging Durable Host Microbe Interaction, Role of Foxp3 Positive Treg, Yasmine Belkaid, PhD, NIAID The Scavenger Receptor CD36 Mediates Macrophage Recognition of the Pathogenic Yeast C. Neoformans, Terry Means, Massachusetts General Hospital Lessons from Poxviruses: The Road from Viral Tropism to Oncolytic Therapy, Grant McFadden, PhD, University of Florida College of Medicine Live Attenuated Influenza Virus Vaccines Based on Modifications of the Viral IFN Antagonistic Gene NS1, Adolfo Garcia-Sastre, PhD, Mount Sinai School of Medicine	10:15 am-Noon
Industry Tutorials	Noon -1:00 pm
Plenary Session Innate Sensing & Signaling Triggering and Controlling Innate Antiviral Immune Defenses Against Pathogenic RNA Viruses, Michael Gale, PhD, University of Washington Role of Nod-like Receptors in Bacterial Recognition and Immunity, Gabriel Nunez, MD, University Michigan The Systemic Autoinflammatory Diseases: Inborn Errors in Innate Immunity, Dan Kastner, MD, PhD, NIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases	1:00 pm - 2:30 pm
Oral Abstract Sessions Fighting Pathogens Novel Regulatory Cells & Mechanisms Immuno-oncology Th17 Cells in Inflammation Genetic Variation & Disease	2:45 pm-4:45 pm
Keynote Session: The Contrasting Roles of IL-15 and IL-2 in the Life and Death of Lymphocytes: Implications for Cancer Therapy and Vaccine Design Thomas Waldman, MD, NIH/NCI/METB	5:00 pm - 5:45 pm
Poster Session with Authors Present	5:45 pm-7:00 pm

Monday, June 9, 2008

Network of Consortia (NOC) Monday: Convergence on a Common Theme

Genomic Variation and the Inherited Basis of Common Disease, David M. Altshuler, MD, PhD, Broad Institute of MIT & Harvard
Genetics of Rheumatoid Arthritis, Peter Gregersen, MD, The Feinstein Institute for Medical Research
Genome-wide Studies in SLE, Tim Behrens, MD, Genentech
The SLEGEN Studies of Lupus Genetics, John Harley, MD, Oklahoma Medical Research Foundation
Genome-wide Association Scan for Type 1 Diabetes, Stephen Rich, PhD, University of Virginia
Collaborative Association Study of Psoriasis, James T. Elder, MD, PhD, University of Michigan
New Allelic Variant Identified in MS, David Hafler, MD, Harvard Medical School
Genetic Variation and the Inherited Basis of Common Disease, Mark Daly, PhD, MIT/Broad Institute, Medical & Population Genetics Program
The Shared Genetic Landscape of Autoimmune Disease, Chris Cotsapas, PhD, The Broad Institute

8:00 am -12:30pm